Hhypophosphatemia in severe burn injury

Background and Aim : Patients with severe burn injury lose a lot of electrolytes, including phosphate. Phosphorous has a pivotal role in intracellular energy metabolism. Many pathophysiologic changes in sever burn such as stress response, ulcer prophylaxis, fluid resuscitation, hyperventilation, burn wound physiology and changes in other electrolytes may be correlated to hypophosphatemia in burn patients. The aim of this study was to evaluate the effect of hypophosphatemia on survival of sever burn patients. Methods : In this cross-sectional study all patients with severe burn injury (≥40% TBSA) hospitalized from May 1 to October 31, 2019 were included. Phosphorus levels on days 3, 7, 14, 21, 28, 35 and 42 extracted from medical records. The correlation between phosphorus level and hospital stay, ventilator dependency, Inhalation injury and mortality calculated by SPSS version 24. P value <05 is considered as significant. Results : Seventy five patients with severe burns (52 males and 22 females) included in this study. Mean of burnt TBSA was 63.3 ± 16.6. The mean age of patients was 31.7 ± 17.1. About half of them had inhalation injury. In-hospital mortality rate was 58.7%. Ventilatory support was indicated in 44 patients (58.7%). We find no correlation between hypophosphatemia on days 3, 7, 14, 21, 28, 35 and 42, and hospital stay, ventilator dependency, Inhalation injury or mortality. Conclusion : While Phosphorous is an important part in intracellular energy metabolism, we cannot find any correlation between hypophosphatemia and survival indices. More prospective studies with a larger sample size are indicated.

کلیدواژه ها:

Burns ، Hypophosphatemia ، Phosphorous ،